← the thesis

What the thesis is built on

Every external source hmm has relied on across its research, memoranda, modelling and comparables. First-party and primary only: regulators and legislation registers, government departments and official datasets, statistics agencies, exchange filings, primary academic literature, standards bodies.

01Regulatory & legal instruments

Australia · enforceable

SourceIssuerIn forceJuris.Supports
Therapeutic Goods Act 1989 (Cth)TGA1991AUPrincipal medical-device / medicines regime
TG Amendment · priority / provisional approvalTGA2018AUExpedited approval pathways
Medical Devices Amendment (2021) · SaMDTGA2021AUSoftware-as-medical-device classification
Medical-device adverse-event reporting (ASDER)TGA2026AUPost-market device surveillance
AusUDID unique device identificationTGA2025AUDevice identification database
Food Standards Australia New Zealand Act 1991FSANZ1991AU/NZFood-standards statute
Food Standards Code 3.2.2AFSANZ2023AUFood-safety management tools mandate
Agricultural & Veterinary Chemicals Code Act 1994APVMA1995AUAgvet chemical registration
Gene Technology Act 2000OGTR2001AUGMO regime
Foreign Acquisitions & Takeovers Act 1975 (FIRB)Treasury / FIRB2021AUNational-security investment screening
Privacy Act 1988 (amended 2024)OAIC1989 / 2024AUData-privacy regime
Safeguard Mechanism (Crediting) Amendment Act 2023Clean Energy Regulator2023AUEmissions baselines / credits
National Electricity RulesAEMC / AEMOstandingAUNEM market rules
Future Made in Australia (CMPTI) Act 2025Treasury / ATO2025AUCritical-minerals production tax incentive
AEMC draft rule · data-centre grid connectionAEMCdraft, 2026AUEnergy system re-regulated for AI demand. A draft rule determination, so it sits outside the counted stack

Japan · enforceable

SourceIssuerIn forceJuris.Supports
PMD Act (Pharmaceuticals & Medical Devices, 145/1960)PMDA / MHLW1961JPBase drug / device statute
PMD Act 2019 amendment · IDATEN / conditional early approvalPMDA2020JPPost-approval model-change protocol
JAS Act (Japanese Agricultural Standards, 175/1950)MAFF1950JPAgricultural standards
Cartagena Act (GMO / biodiversity, 97/2003)MAFF/METI/MEXT2004JPGMO biosafety
Food Labelling Act (70/2013)Consumer Affairs Agency2015JPFood labelling
Food Sanitation Act · HACCP mandate (233/1947)MHLW2020JPMandatory HACCP hygiene
Economic Security Promotion Act (43/2022)Cabinet Office / METI2022JPCritical-minerals designation
APPI (Personal Information Protection, 57/2003, 2020 amdt)PPC2022JPData privacy
FIT / FIP Renewable Electricity Act (108/2011)METI2012JPFeed-in tariff / premium
GX Promotion Act (32/2023)METI2023JPDecarbonised-growth transition
AI Promotion Act (53/2025)Cabinet Office (AI Strategy HQ)2025JPAI strategy framework
Basic Act on Food, Agriculture & Rural Areas (revised)MAFF2024JPFood security made statutory
Food Supply Emergency Measures ActMAFF2024JPFood-security emergency powers
Smart Agriculture Technology Promotion ActMAFF2024JPCertified smart-ag plans register

New Zealand · enforceable

SourceIssuerIn forceJuris.Supports
Medicines Act 1981Medsafe1981NZMedicines / devices interim regime
Medicines (Database of Medical Devices) Regs 2003 · WANDMedsafe2003NZPost-market device notification
Hazardous Substances & New Organisms Act 1996EPA1996NZGMO / new-organism gate
Agricultural Compounds & Vet Medicines Act 1997MPI2001NZAgri-compound approval
Animal Products Act 1999MPI1999NZAnimal-product risk management
Food Act 2014MPI2016NZRisk-based food control
Privacy Act 2020OPC2020NZData privacy
Climate Change Response Act 2002, Pt 4 · NZ ETSEPA2008NZEmissions trading
Electricity Industry Act 2010Electricity Authority2010NZElectricity market
Therapeutic Products Act Repeal Act 2024NZ Parliament2024NZRepeal of TPA 2023

Global / cross-border · why-now context

SourceIssuerIn forceJuris.Supports
How AI is used in FDA-authorized medical devicesSingh, Bapna, Diab, Ruiz & Lotter · npj Digital Medicine1 Jul 2025US33 authorisations 1995 to 2015 at a maximum of 6 a year; 1,016 authorisations across 736 unique devices to December 2024
Three Decades of FDA Authorizations of AI/ML-Enabled Medical DevicesGolshani & Joseph · Cureus 18(7) e11258313 Jul 2026US1,430 authorisations September 1995 to December 2025, and 331 in 2025 alone
FDA PCCP final guidanceFDA2024USPost-approval model-change route
CMS hospital-at-home reimbursement waiverCMS2020USThe route by which hospital-level care at home is paid for
IRA Section 45X (domestic-content credit)US Treasury / IRS2022USEnergy manufacturing incentive
BIOSECURE ActUS Congress2025USBiotech supply-chain shift
EU AI Act (high-risk class)European Commission2024EUAI regulation direction
EU Critical Raw Materials ActEuropean Commission2024EUCritical-minerals policy
ICH Q13 continuous manufacturingICH2023GlobalPharma manufacturing standard
WHO Listed Authority tiers / GBT maturity (ML3/ML4)WHO2022 / 2026GlobalRegulatory-maturity screening
PIC/S GMP mutual reliancePIC/SstandingGlobalGMP recognition
Access Consortium relianceAccess Consortium2020CA / UKRegulatory reliance pathways

Frameworks & voluntary guidance

SourceIssuerIn forceJuris.Supports
Critical Minerals Strategy 2023-2030DISR2023AUDirection of travel, minerals
Australia's AI Ethics PrinciplesDISR2019AUVoluntary AI principles
Voluntary AI Safety StandardDISR / NAIC2024AUVoluntary AI standard
METI AI Governance Guidelines v1.1METI2022JPAI governance guidance
PMDA AI/ML Medical Device Evaluation GuidancePMDA2023JPAI-SaMD evaluation
DASH for SaMD / SaMD 2MHLW / PMDA2020 / 2023JPSaMD acceleration strategy
METI Critical Minerals StrategyMETI2023JPSupply-assurance policy
Algorithm Charter for Aotearoa NZStats NZ2020NZVoluntary algorithm charter
Critical Minerals List & StrategyMBIE / NZP&M2024NZMinerals policy + list
FSANZ 2030 Roadmap / novel foodsFSANZ2025AU/NZNovel-food approval pathway
TGA AI Review outcomes reportTGA2026AUAI-SaMD regulatory review

02Academic & scientific literature

Peer-reviewed anchors.

SourceAuthor(s)In forceVenueSupports
Effects of exclusivity on commercialisationGaessler & Wagner2022Rev. Econ. & Stat.Reinforces patent-clock causality
Demographics and AutomationAcemoglu & Restrepo2022Rev. Econ. StudiesAcemoglu and Restrepo find that an ageing workforce raises automation innovation, measured on Japan among other economies.
Induced Innovation / factor scarcityHayami & Ruttan1970J. Political EconomyLabour scarcity pulls labour-saving agtech
Artificial Intelligence and Economic GrowthAghion, Jones & Jones2017NBERAI value concentrates in essential Baumol sectors
Macroeconomics of unbalanced growth (cost disease)Baumol1967AERCost-disease diagnosis
Baumol's cost disease revisitedNordhaus2008·Cost-disease confirmation in US data
What drives health-care expenditure? Baumol's modelHartwig2008J. Health EconomicsCost disease in OECD health spend
Innovation & regulation pioneer time-penaltyStern2017J. Public EconomicsStern measures a 34% time penalty on the pioneer of a regulated technology, and the same regulatory path then excludes followers.
Regulatory arbitrage & institutional qualityHouston, Lin & Ma2012J. FinanceArbitrage pays only in strong institutions
Learning curves / Wright's lawFarmer & Lafond2016Research PolicyEnergy-hardware cost forecastability
Empirically grounded technology forecasts (energy)Way et al.2022JouleEnergy cost-trajectory anchor
A Model of Growth Through Creative DestructionAghion & Howitt1992EconometricaEntrants capture disruption rents
Income and health spending (elasticity ~0.7)Acemoglu, Finkelstein & Notowidigdo2013Rev. Econ. & Stat.Necessity-demand persistence (health)
The Value of Life and the Rise in Health SpendingHall & Jones2007QJEHealth share rises with income
Money chasing deals?Gompers & Lerner2000J. Financial EconomicsCapital inflows inflate entry valuations
What drives private equity fund returns?Diller & Kaserer2009Eur. Financial Mgmt"Money chasing deals" drags returns
Private Equity PerformanceKaplan & Schoar2005J. FinanceBoom-vintage funds underperform
Borrow Cheap, Buy High?Axelson, Jenkinson, Strömberg & Weisbach2013J. FinanceAxelson, Jenkinson, Strömberg and Weisbach find that higher purchase prices lead to lower returns on the same deals.
Investment cycles and startup innovationNanda & Rhodes-Kropf2013J. Financial EconomicsHot-market entrants fail more, win bigger
The Regulation of EntryDjankov, La Porta, Lopez-de-Silanes & Shleifer2002QJEEntry regulation as incumbent protection
Does regulation reduce innovation?Aghion, Bergeaud & Van Reenen2023AERRegulation cuts innovation 5.7%, hits small firms
Health-IT adoption and hospital costsAgha2014J. Health EconomicsPrior "tech fixes healthcare" wave failed
The Simple Macroeconomics of AIAcemoglu2025·Acemoglu estimates the addition of AI to total factor productivity at 0.66% or less over a decade.
The Productivity J-CurveBrynjolfsson, Rock & Syverson2021AEJ: MacroeconomicsGPT gains lag a fund's 10-year clock
How AI is used in FDA-authorized medical devicesSingh, Bapna, Diab, Ruiz & Lotter · npj Digital Medicine2025US1,016 AI-enabled device authorisations across 736 devices to December 2024

03Government & institutional datasets

SourceIssuerIn forceJuris.Supports
FDA AI-Enabled Medical Devices listFDA2026USThe authorisation table by decision date. It publishes no annual count, which is why the series above is cited to the two peer-reviewed counts
Energy and AI (WEO special report)IEA2025GlobalData-centre electricity demand ~945 TWh by 2030
Precision Agriculture in the Digital Era (EIB-248)USDA ERS2023USPrecision-ag / autosteer adoption
Labour Force Australia, Detailed (6291.0.55.001)Australian Bureau of Statistics2026AUAU agricultural-labour contraction
2020 Census of Agriculture & ForestryMAFF / Statistics Japan2020JPJP farmer counts & ageing structure
World Bank indicators (health/agri %GDP, energy)World Bank2026GlobalMarket-sizing baselines AU/JP/NZ/US
WHO NRAs at ML3/ML4 & Transitional WLA listsWHO2026GlobalRegulatory-maturity screening
TGA ARTG datasets / registerTGA·AUAU device / AI-device register
ANZCTR clinical-trials registryANZCTR·AU/NZAU/NZ trial-registration activity
Primary legislation registers (portal infrastructure)legislation.gov.au; .govt.nz; e-Gov Japan; regulators·AU/JP/NZEnacted-instrument register infrastructure
Care-worker shortage projection (570k by 2040)MHLW·JPCare-sector demographic forcing
EDINET (securities-registration filings)FSA Japan2024JPPre-IPO share-issuance / step-up series
Global Innovation Index 2025, Australia profileWIPO2025AUAustralia 22nd overall, 18th on innovation inputs, 30th on outputs; production and export complexity and labour productivity growth its listed weaknesses
Medicines MatterMedicines Australia2016-21 seriesAURegistration to a Pharmaceutical Benefits Scheme listing at 466 days on new molecular entities registered 2016 to 2021, against a 384-day average across twenty OECD countries
Cochlear implantsNational Institute on Deafness and Other Communication DisordersDec 2019 countGLApproximately 736,900 registered devices implanted worldwide by December 2019, across all manufacturers
Mineral Commodity Summaries 2026, nitrogenUnited States Geological Survey2026 editionGL156 million tonnes of contained nitrogen synthesised in 2024, the revised figure in the 2026 edition

04Market, financial & valuation data

Named commercial providers are the primary data pull; some are sales-gated, so only official pages are linked.

SourceProviderIn forceJuris.Supports
Damodaran datasets (NYU Stern)Aswath DamodaranannualUS/globalValuation cross-check / discount-rate anchor
State of Private MarketsCarta2025-26USUS seed post-money median (USD 24M, Q4 2025)
Valuations / vertical / Digital-Health / Climate reportsPitchBook2025-26GlobalRound-by-round valuation benchmarks
Reference dataset (company universe, funding, acquirers)Crunchbase2026GlobalCompany universe, funding, acquirer data
Seed data (markup relationship)AngelList·USSeed quintile markup relationship
State of Australian Startup FundingCut Through Venture / Folklore Ventures2025-26AUAU seed median (around AUD 16.0M); exit-route mix and exit crunch; sector funding
Australia Outliers Report 2026Side Stage Ventures / Dealroom2026AUJune 2026 edition: 1.09 companies above USD 1B and 0.16 above USD 10B, per USD 1B of venture invested since 2000. First of the hubs compared on the second, third on the first
New Zealand venture and startup datasetDealroom.co / NZ Growth Capital Partners2026NZNew Zealand capital efficiency, enterprise value per venture dollar at 10.89x; the startup funnel; sector funding
Startup survey, six-country listing comparisonMETI / PwC / JVCA2026JPJP exit structure (IPO-led, TSE Growth); cross-country M&A / IPO
Japan Startup FinanceINITIAL / Speeda (Uzabase)2025JPJP seed valuations, M&A, step-up
Research on Speeda dataJapan Investment Corp2025JPJP seed medians under USD 7M, flat 2021 to 2025
Digital-health fundingRock HealthquarterlyUSDigital-health round benchmarks
Healthcare Investments & ExitsSilicon Valley BankannualUSHealth-sector exit benchmarks
New Energy Outlook / cost dataBloombergNEF·GlobalEnergy / climate pricing context
Global Secondary Market ReviewJefferies2025Global2025 secondary volume (around USD 240B)
Secondary Market ReportLazard2024-25GlobalSecondary volume (USD 233B, 2025)
Secondary Market OverviewCampbell Lutyens2025GlobalSecondary volume (USD 225B, 2025)
Open Source VC databasesAirtree·AUAU Series A/B downstream-capital bench
AgriFoodTech / deep-tech venture reportsAgFunder; S2G; DCVC·GlobalAgri/food & deep-tech venture context
Loss-ratio study (via Chicago Booth)Correlation Ventures·USBiotech 36% vs internet 59% loss ratio
Asia-Pacific Private Equity ReportBain & Company2025APACRegional PE / exit-market context
SE-Asia Tech InvestmentCento Ventures2024SE AsiaRegional venture context (comparison set)
Global VC Terms ReportMorrison Foerster2025GlobalVenture terms benchmarks
VC Fund Performance (quarterly); Founder Ownership; State of Pre-SeedCarta2024-25USFund-performance, dilution and pre-seed benchmarks

05Company, exit & comparables data

SourceProviderIn forceJuris.Supports
Reference dataset (22,217 cos, classified)Crunchbase base + hmm classifier2026APACThe base of liquidity events, bucketed from USD 100M upward.
Company universe export (enriched)Crunchbase / LinkedIn / G2 / SimilarWeb, enriched on a commercial B2B data platform2026AU/JP/NZIn-mandate company universe
Exit cohort · 243 named liquidity events (w/ source URLs)hmm (primary-sourced)2026AU/JP/NZRealised M&A + listing exit base
ASX / NZX filings & listingsASX; NZX·AU/NZIPO listings, market cap at listing
JPX / TSE Growth listingsJapan Exchange Group·JPJP IPO tail
NZ Takeovers Panel recordsTakeovers Panel (NZ)·NZNZ M&A / takeover confirmations
JP startup M&A / IPO databasesfirstcvc.jp; ipokabu.net; minkabu.jp; STARTUP DB·JPJP small-M&A exits (under-covered)
M&A dataRECOF / MARR·JPJP startup M&A deal records
M&A / IPO announcements (press wires)BusinessWire; PR Newswire; Cision·GlobalPrimary deal announcements
Company investor-relations releasesportfolio / acquirer IR pages··Deal terms cross-checked to primary
Regulated-software M&A comps (17 deals)SEC filings / LSE RNS / proxies / IR2023-25US/UKIndicative multiples for IM Appendix B (median EV/Rev 7.22x; small US/UK sample read across to AU/JP/NZ)
Realised exit-value pull (outstanding)Mergermarket / Capital IQ / DealForma / IJGlobal·GlobalRealised M&A / listing $ values
Wireless LAN patent licensingCSIROto 2016AUAround AUD 430M returned across more than 20 international licence agreements
Pulse oximetry, company historyNihon Kohden1972JPThe pulse-oximetry principle conceived at Nihon Kohden in 1972. The company's pages give 1972 and 1974 for the patent and name no month
Amchepry approvalSumitomo Pharma · MHLW6 Mar 2026JPThe first induced pluripotent stem cell medicine, approved conditionally and for seven years. Two iPS-derived products were approved that day on the same limit
P5 collar, state approvalsHalterFeb and Jul 2026AUApproved in Victoria in February 2026 and in South Australia in July 2026, each a state approval under amended animal welfare regulations

06Books, essays & named frameworks

SourceAuthorIn forceFieldSupports
Engel's law (food-demand share falls with income)Ernst Engel1857EconomicsNecessity-demand inescapability (Eat)
Wright's law (learning curve)T. P. Wright1936Aeronautics / econForecastable hardware cost decline (Power)